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Bone and Joint Manifestations of Inflammatory Bowel Disease Spondyloarthropathy Axial skeleton Sacroiliitis Ankylosing spondylitis Peripheral Type 1 (oligoarticular) Type 2 (polyarticular) (rare) Abbreviations: CD, Crohn disease

NSAIDs like ibuprofen can impair renal function, especially in dehydrated states, potentially leading to acute kidney injury